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As previously shown, DPI induced progressive cell death over the three-day observation period, which was significantly mitigated by downregulation of MYCN (16) ( Figure 1C )

The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice

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All statistical analyses were performed using GraphPad Prism v7.0 (GraphPad Software, La Jolla, CA, USA)